职称/职务

副教授/硕士生导师，化生系副主任

研究方向

1、食品安全与质量控制

2、细胞与活体分析

3、生化传感

4、先进分离材料与装置

邮箱

wangss17@ahut.edu.cn

学习工作经历

2017/11－至今，bat365官网登录，我院，副教授；

2015/11－2017/10，南京大学基础医学博士后流动站，博士后；

2011/09－2015/08，南京大学，我院，博士

主要科研项目及成果

王双寿，博士，硕士生导师，化学生物学与制药工程系副主任，bat365官网登录青年拔尖人才。主要从事食品安全、环境监测与生命分析化学相关领域新材料、新器件、新方法的开发与应用研究。主持国家自然科学基金、安徽省自然科学基金、安徽省高校研究计划重点项目等各类项目10余项，作为主要参与人参加国家重大科研仪器研制项目和国家自然科学基金面上项目各1项。以第一作者和/或通讯作者在Nature Protocols, Journal of Hazardous Materials，Sensors and Actuators: B. Chemical，ACS Applied Materials & Interfaces, Chemical Science, Analytical Chemistry等国际著名学术期刊发表SCI/EI收录论文30余篇。申请国家发明专利8项。曾获中国分析测试协会科学技术奖（CAIA奖）一等奖1项（编号：2017-1-001-R，7/9）、《2017年度中国博士后科学基金资助者选介》特别介绍1次（全国每年遴选100人）。现任国际学术期刊《Beverage Plant Research》、《Chinese Journal of Structural Chemistry》和《Advanced Powder Materials》青年编委和客座编辑以及《Frontiers in Chemistry》特邀评审编辑（Review Editor）等职。指导学生获挑战杯、互联网+等竞赛获省级及以上奖项3项。

承担项目经历：

1.国家自然科学基金青年项目，2020.01-2022.12，21904003，25万，主持；

2.bat365官网登录‘青年拔尖计划-青年英才’人才项目，2021.01-2025.12，20万，主持；

3.安徽省自然科学基金青年项目，2019.01-2021.12，1908085QB66，10万，主持；

4.安徽省高校研究计划重点项目，2022.12-2024.12，2022AH050296, 10万，主持；

5. bat365官网登录人才引进科研启动经费，20万，在研，主持；

6.安徽省生化药物工程技术研究中心, 开放课题, 2022SYKFZ02, 2022.01-2023.12, 5万元，主持；

7.南京大学“生命分析化学国家重点实验室”开放研究基金，SKLACLS1801，2018.03-2019.12，5万，主持；

8. bat365官网登录校青年基金项目，QZ201807，2019.01-2020.12, 0.8万，主持；

9.中国博士后科学基金特别资助项目，2017T100346，2017.01-2017.12，15万，主持；

10. 中国博士后科学基金面上资助项目，2016M591811，2016.03-2016.12，5万，主持；

11. 国家重大科研仪器研制项目，21627810，2017.01-2021.12，555万，参加；

12. 国家自然科学基金面上项目，21275073，2013.01-2016.12，80万，参加

近期发表的科研论文:

1. Shuangshou Wang,* Lu Zhang, Haili Wang, Yu Wu, Mingfu Ye, Tingxuan Yan, Yang Chen, Tao Ma, Jin Ye. Halochromy incorporated with inner filter effect-based fluorescence quenching: A dual-response strategy for spoilage sensing of proteinous foods with rapid and irreversible readout. Sensors & Actuators: B. Chemical. 2024, 409, 135631.

2. Yansong Zhang, Yihan Ding, Yidan Ma, Zixin Zhang, Yipei Wang, Daojin Li, Shuangshou Wang,* High-capacity boronate affinity-based template-immobilized surface imprinted silica nanoparticles for rapid, selective, and efficient extraction and determination of lincomycin in milk and chicken. Front. Sustain. Food Syst. 2023, 7, 1271921.

3. Yansong Zhang, Zixin Zhang, Yihan Ding, Daojin Li, Shuangshou Wang,* Boronate affinity-based clindamycin-imprinted magnetic nanomaterials for rapid, efficient and selective extraction and determination of clindamycin in animal-derived food. New J. Chem., 2023, 47, 17843

4. Shuangshou Wang,* Yuwen Ding, Lu Zhang, Yingle Cheng, Ying Deng, Qin Jiang, Hongrui Gao, Jing Gu, Ganggang Yang, Lei Zhu, Tingxuan Yan, Qi Zhang,* Jin Ye.* Combination of colorimetry, inner filter effect-induced fluorometry and smartphone‑based digital image analysis: A versatile and reliable strategy for multi-mode visualization of food dyes. Journal of Hazardous Materials, 2023, 445, 130563.

5.Shuangshou Wang,* Haili Wang, Zhihong Yuan, Mengyao Li, Hongrui Gao, Liangjingjing Shan, Aowei Li, Yuwen Ding, Jing Gu, Lei Zhu, Tingxuan Yan, Mingfu Ye,* Jin Ye.* Colorimetry combined with inner filter effect-based fluorometry: A versatile and robust strategy for multimode visualization of food dyes. ACS Applied Materials & Interfaces, 2022, 14, 57251-57264.

6.Shuangshou Wang,* Wenzhi Li, Zhihong Yuan, Qiwen Jin, Zongpeng Ding, Xiaomeng Liu, Mingfu Ye, Jing Gu, Tingxuan Yan, Hongmei Chen,* Yang Chen.* Semiquantitative naked-eye detection of synthetic food colorants using highly-branched pipette tip as an all-in-one device. Analytica Chimica Acta, 2022, 1211, 339901.

7. Shuangshou Wang,* Lu Zhang, Qiwen Jin, Zhongqiu Xu, Jiayi Zhao, Yuwen Ding, Wenzhi Li, Peng Lin, Jing Gu, Qi Zhang,* Yang Chen, Hongmei Chen, Tingxuan Yan.* Filter paper-based colorimetric analysis: An instrument-free strategy for semiquantitative naked-eye detection of food colorants. Food Chemistry, 2022, 390, 133087.

8. Shuangshou Wang,* Haili Wang, Yuwen Ding, Wenzhi Li, Hongrui Gao, Zongpeng Ding, Peng Lin, Jing Gu, Mingfu Ye, Tingxuan Yan, Hongmei Chen,* Jin Ye.* Filter paper- and smartphone-based point-of-care tests for rapid and reliable detection of artificial food colorants. Microchemical Journal, 2022, 183, 108088.

9. Tingxuan Yan,* Haili Wang, Xingfang Song, Tingyuan Yan, Yuwen Ding, Kang Luo, Juan Zhen, Gui He, Libin Nian, Shuangshou Wang,* Zhixiang Wang.* Fabrication of apigenin nanoparticles using antisolvent crystallization technology: A comparison of supercritical antisolvent, ultrasonic-assisted liquid antisolvent, and high-pressure homogenization technologies. International Journal of Pharmaceutics, 2022, 624, 121981.

10.Shuangshou Wang,* Yuwen Ding, Haili Wang, Wenzhi Li, Wenjing Xu, Panwen Sun, Wei Huang, Yang Chen,* Jing Gu, Peng Lin, Liang Ma, Zi Liu, Qiang Ling, Qi Zhang, Hongmei Chen, Tingxuan Yan.* Molecularly imprinted upconversion nanoparticles for active tumor targeting and microinvasive photothermal therapy. Journal of Materials Science, 2022, 57, 5177-5197.

11. Hongmei Chen,* Guosheng Peng, Yong Li, Shuangshou Wang,* Changmin Lin.* Clinical immunofluorescence comparison analysis of microfluidic chips for highly efficient detection of CTCs with colorectal cancer and other cancers. Microfluidics and Nanofluidics, 2022, 26, 62.

12. Haili Wang, Feng Li, Shuwen Liu, Shuangshou Wang.* Colorimetric paper-based visual point-of-care tests of artificial food colorants. Journal of Guizhou Normal University, 2023, 41, 77-84.

13. Tingxuan Yan, Yuting Tao, Xiangxiang Wang, Changling Lv, Guizhi Miao, Shuangshou Wang*, Deqiang Wang*, Zhixiang Wang*. Preparation, characterization and evaluation of the antioxidant capacity and antitumor activity of myricetin microparticles formated by supercritical antisolvent technology. The Journal of Supercritical Fluids, 2021, 175, 105290.

14. Shuangshou Wang*, Zhendong He, Wenzhi Li, Jiayi Zhao, Tong Chen, Shimin Shao, Hongmei Chen*. Reshaping of pipette tip: A facile and practical strategy for sorbent packing-free solid phase extraction. Analytica Chimica Acta, 2020, 1100, 47-56.

15. Shuangshou Wang*, Wenzhi Li, Panwen Sun, Zhongqiu Xu, Yuwen Ding, Wenjing Xu, Wei Xu,Jing Gu*, Selective extraction of myoglobin from human serum with antibody-biomimetic magnetic nanoparticles. Talanta, 2020, 219, 121327.

16. Hongmei Chen*, Yong Li, Zhifeng Zhang, Shuangshou Wang*, Immunomagnetic separation of circulating tumor cells with microfluidic chips and their clinical applications. Biomicrofluidics, 2020, 14, 041502.

17. ShuangshouWang*, Xiaomei Lu, Jie Cheng, Qiongqiong Ge. Advance in boronate affinity-based controllable oriented surface imprinting. Chin. Sci. Bull., 2019, 64, 1340-1351.

18. Rongrong Xing†, Shuangshou Wang†, Zijun Bie, Hui He, Zhen Liu*, Preparation of molecularly imprinted polymers specific to glycoproteins, glycans and monosaccharides via boronate affinity controllable oriented surface imprinting, Nature Protocols, 2017, 12, 964-987. (IF 17.021, 共同一作).

19. Shuangshou Wang, Yanrong Wen, Yijia Wang, Yanyan Ma, Zhen Liu*, Pattern recognition of cells via multiplexed imaging with monosaccharide-imprinted quantum dots. Analytical Chemistry, 2017, 89, 5646-5652.

20. Shuangshou Wang, Jin Ye, Xinglin Li, Zhen Liu*, Boronate affinity fluorescent nanoparticles for Förster resonance energy transfer inhibition assay of cis-diol biomolecules. Analytical Chemistry, 2016, 88, 5088-5096.

申请专利：

1. 王双寿; 何振东; 邵士民; 陈桐; 一种基于二次成形的移液器吸头、制备方法及应用, 2021-06-04, 发明专利, ZL201911154006.3

2. 王双寿; 张璐; 晋琪稳; 许中秋; 赵家怡; 卢小媚; 颜庭轩; 陈红梅; 一种饮料色素目测比色卡、制备方法及其应用, 2021-9-24, 发明专利, ZL202111122156.3

3. 王双寿; 李文治; 袁智宏; 卢小媚; 颜庭轩; 陈红梅; 一种基于逐层可控支化改性的移液器吸头、制备方法及其应用, 2021-10-20, 发明专利, ZL202111220893.7

4. 王双寿; 张璐; 李凤; 刘淑雯; 王煜程; 何梓瑞; 纪曦文; 一种食品色素快速检测装置, 2022-12-12, 实用新型专利, ZL202223343230.7

5. 王双寿; 王海丽; 丁玉雯; 李文治; 颜庭轩; 陈红梅; 一种上转换荧光人工抗体、制备方法及其应用, 2021-10-21, 发明专利, 202110719357.5

6. 王双寿; 王海丽; 袁智宏; 高鸿瑞; 单亮晶晶; 卢小媚; 颜庭轩; 食品色素的双模比色检测荧光试纸及其制备方法和应用, 2022-09-13, 发明专利, 202210837391.7

7. 王双寿; 王海丽; 李文治; 丁玉雯; 晋琪稳; 卢小媚; 颜庭轩; 一种食品色素的多模裸眼检测数字化颜色信息卡、制备方法及其应用, 2022-07-08, 发明专利, 202210588143.3

9. 王双寿; 王赞; 孙畅畅; 陈金柱; 李凤; 王煜程; 何梓瑞; 王艺函; 何永兴; 一种染料废水脱色与色素残留量实时指示二合一装置, 2023-11-09, 实用新型专利, 2023230530707